Laboratory of Neurobiology of Vision

Head: Wioletta Waleszczyk


Staff: Piotr Dzwiniel (PhD student); Katarzyna Kordecka (PhD student), Jan Popiołkiewicz (PhD student), Ida Raciborska (PhD student), Paulina Urban


Research profile:


Our activity focuses on both basic and translational visual research. Basic studies focus on information processing and plasticity in the visual system. Coding of the visual information, parallel processing in the visual system, function of the extrageniculate visual pathway, are of particular interest. Plasticity following damage of the visual pathway as well as induced by visual and electrical stimulation are investigated. Translational studies concern rehabilitation of visual dysfunctions with a use of various methods: visual stimulation, noninvasive current stimulation, gene therapy.




  • single-, multi-unit and LFP/EP recordings from subcortical and cortical visual structures in animals; EEG/EP recordings in human;
  • noninvasive current stimulation;
  • gene therapy;
  • visual training;
  • behavioral training;
  • neuroinformatic analysis of electrophysiological signals, spike train analysis and modeling.


Current research activities:


  • the role of the extrageniculate visual pathway (response properties of visual neurons, spontaneous and visually evoked oscillatory activity, information coding, brain state-dependent modulation of neuronal activity);
  • methods of rehabilitation of visual dysfunctions: visual training, noninvasive current stimulation;
  • mechanisms of plasticity in the visual system following damage (retinal lesion, stroke, neurodegeneration).


Selected publications:


Waleszczyk WJ, Nagy A, Wypych M, Berényi A, Paróczy Z, Eördegh G, Ghazaryan A, Benedek G. (2007) Spectral receptive field organization of neurons in the superior colliculus. Exp. Brain Res., 181:87-98.


Young JM, Waleszczyk WJ, Wang C, Calford MB, Dreher B, Obermayer K. (2007)
Cortical reorganization consistent with spike timing- but not correlation-dependent plasticity. Nature Neurosci., 10:887-95.


Wójcik DK, Mochol M, Jakuczn W, Wypych M, Waleszczyk WJ. (2009) Direct estimation of inhomogeneous Markov interval models of spike-trains. Neural Comput. 21:2105-13.


Mochol G, Wójcik DK, Wypych M, Wróbel A, Waleszczyk WJ. (2010) Variability of visual responses of superior colliculus neurons depends on stimulus velocity. J. Neurosci., 30:3199-3209.


Wypych M, Wang C, Nagy A, Benedek G, Dreher B, Waleszczyk WJ. (2012) Standardized F1 - A consistent measure of strength of modulation of visual responses to sine-wave drifting gratings. Vision Res. 72:14-33.


Wypych M, Nagy A, Mochol G, Foik A, Benedek G, Waleszczyk WJ. (2014) Spectral characteristics of phase sensitivity and discharge rate of neurons in the ascending tectofugal visual system. PLoS One. 9(8):e103557.


Foik AT, Kublik E, Sergeeva EG, Tatlisumak T, Rossini PM, Sabel BA, Waleszczyk WJ. (2015) Retinal origin of electrically evoked potentials in response to transcorneal alternating current stimulation in the rat. Invest Ophthalmol Vis Sci. 56:1711-1718.