Laboratory of Psychophysiology

Head: Anna GRABOWSKA

Staff: Katarzyna Chyl (Phd student), Agnieszka Dębska, Katarzyna Jednoróg, Agnieszka Kacprzak (koordynator ds. Maestro), Emilia Kolada (Phd student), Ilona Kotlewska-Waś (Phd student), Magdalena Łuniewska (Phd student), Anna Nowicka, Maria Nowicka (Phd student), Krystyna Rymarczyk, Iwona Szatkowska, Aleksandra Zasada (Technician), Łukasz Żurawski (Phd student)



Research profile

The research is focused on neural correlates of higher mental functions in man using neuropsychological, neurophysiological and behavioral approaches. The topics involve issues ranging from basic mechanisms of attention and emotion through functional architecture of memory to self-consciousness. The main goal of studies performed on healthy human subjects, patients with brain injuries, patients with neurodegenerative (Parkinson’s and Alzheimer’s diseases) and neurodevelopmental disorders (dyslexia, ADHD) is to get a better insight into the mind-brain relationship and to provide knowledge contributing to elaboration of better tools for clinical diagnosis and remediation. More information about laboratory on the web page Laboratory of Psychophysiology

Methods:

• neuroimaging and electrophysiological methods are used enabling monitoring brain functions with high spatial and temporal resolution (functional Magnetic Resonance Imaging/Voxel Based Morphometry and Event-Related Potentials/Electromiography, respectively). These meth- ods are coupled with studies of the effects of focal brain lesions upon cognitive and/or emotional performance
• recent studies focus more on “functional integration” (connectivity) rather than functional localization using diffusion tensor imaging (DTI) and structural equation modeling (SEM).

Current research activities

• processing of self-related information
• neural organization of deception: an fMRI investigation in healthy subjects
• neural correlates of unconscious processing in neglect patients
• fMRI study of emotional aspect of false memory
• electrophysiological correlates of dyslexia: behavioral and ERP study of attention, magnocellular, phonological and cerebellar dysfunctions
• neuroanatomical markers of dyslexia: functional and structural magnetic resonance imaging studies
• the effect of motivation on working memory: behavioral investigation of patients with orbitofrontal damage and an fMRI study of healthy subjects
EMG study of dynamic and static emotional expression and its relation to self – reported empathy
• neural mechanisms underling intentional forgetting of neutral and emotional stimuli
• neural correlates of cognitive dysfunction in Parkinson’s disease

Selected publications

Marchewka A., Jednoróg K., Falkiewicz M., Szeszkowski W., Grabowska A., Szatkowska I. (2012) Sex, lies and fMRI-gender differences in neural basis of deception. PLOS ONE, 7(8): e43076.

Grabowska A., Marchewka A., Seniów J., Polanowska K., Jednoróg K., Królicki L., Kossut M., Członkowska A. (2011) Emotionally negative stimuli can overcome attentional deficits in patients with visuo-spatial hemineglect. Neuropsychologia, 49: 3327-3337.

Szatkowska I., Szymańska O., Marchewka A., Soluch P., Rymarczyk K. (2011) Dissociable contributions of the left and right posterior medial orbitofrontal cortex in motivational control of goal-directed behavior. Neurobiology of Learning and Memory, 96: 385-391.

Jednoróg K., Marchewka A., Tacikowski P., Heim S., Grabowska A. (2011) Electrophysiological evidence for the magnocellular- dorsal pathway deficit in dyslexia. Developmental Science, 14: 873–880.

Nowicka A., Marchewka A., Jednoróg K., Tacikowski P., Brechmann A. (2011) Forgetting of emotionally negative stimuli is hard: fMRI study of directed forgetting. Cerebral Cortex, 21: 539-549.