IBD lectures

Lectures in biochemistry and molecular biology 2016/2017

From molecule to cell

 

Wednesdays 9-10 am

The Conference Room of the Nencki Neurobiology Centre

Literature

 

  1. Integrative cellular physiology

        1. Cellular structure, signaling and function

  • Structure and function of proteins (S. Pikuła) October 12, 2016
  • Protein synthesis (M. Dziembowska) October 19, 2016
  • Posttranslational modifications of proteins and their functional significance (A. Filipek) October 26, 2016
  • Structure and function of cellular membranes (K. Kwiatkowska) November 2, 2016
  • Exocytic pathways in eukaryotic cells (T. Prószyński) November 9, 2016
  • Endocytosis (M. Miączyńska) November 16, 2016
  • Transport through biological membranes (K. Nałęcz) November 23, 2016
  • Mitochondrial ion channels - from structure to function (A. Szewczyk) November 30, 2016
  • Bioenergetics (K. Zabłocki) December 7, 2016
  • Principles of intracellular calcium signaling (K. Zabłocki) December 14, 2016
  • Microtubules and microtubule-based structures (D. Włoga) December 21, 2016
  • Molecular mechanisms of cell motility – molecular motors (A. Kasprzak) January 11, 2017 (9 a.m.)
  • Mechanisms of cellular migration (J. Rędowicz) January 11, 2017 (10 a.m.)

 

2. Cell cycle and cell fate

  • Cellular senescence – the mechanism and the role in organismal aging and age-related diseases (G. Mosieniak) January 18, 2017
  • Autophagy and cell death – molecular mechanisms and function (I. Ciechomska) January 25, 2017
  • Molecular mechanisms of cancerogenesis – the current view (K. Piwocka) February 1, 2017

 

Exam February 8, 2017

 

Break

 

  1. Genetic information
  • Nuclear organization of the genome – from structure to function (G. Wilczyński) March 1, 2017
  • Regulatory mechanisms of transcription (B. Kamińska) March 8, 2017
  • Transcriptional factors (T. Wilanowski) March 15, 2017
  • Epigenetic mechanisms of regulation of gene expression (B. Kamińska) March 22, 2017
  • DNA methylation in control of gene expression (W. Leśniak) March 29, 2017

 

  1. From cell signaling to the system
  • Determinants of aging and longevity (E. Sikora) April 5, 2017
  • Cellular stress response – the role in physiology and disease (K. Piwocka) April 12, 2017
  • Dysfunction of mitochondria and their effects for the cell (J. Szczepanowska) April 19, 2017

     

 

  1. Methods in cell biology, tissue engineering
  • Imaging of structures and processes in cells and tissues (G. Wilczyński) April 26, 2017
  • Imaging of cellular signaling (T. Bernaś) May 10, 2017
  • Induced pluripotent stem cells and tissue engineering (U. Wojda) May 17, 2017
  • Genetic modifications of rodents (A. Klejman) May 24, 2017
  • Inducible gene expression in transgenic animals (W. Konopka) May 31, 2017
  • Regulatory genomics/bioinformatics (M. Dąbrowski) June 7, 2017

 

Exam June 14, 2017

 

 

 

 

Lectures in neuroscience 2015/2016

Wednesdays 9-10 am

The Conference Room of the Nencki Neurobiology Centre

 

 

 

 

Neurons

  • Introduction: what is neuroscience, history, from molecules to brain. ; B: 1 P: 1; P. Boguszewski; 2015-10-07
  • Cells of the Nervous System: Neurons and glia; B: 2 P: 1; M. Skup; 2015-10-14
  • Electrical Signals of Nerve Cells; B: 3,4  P: 2-4; P. Boguszewski; 2015-10-21
  • Synaptic Transmission; B: 5 P: 5; M. Skup; 2015-11-04
  • Neurotransmitter Systems: Neurotransmitters and Their Receptors ; B: 6 P: 6; P. Boguszewski; 2015-11-18
  • The blood – brain barrier ; K: App D + TBA; K. Nałęcz; 2015-11-25
  • Molecular Signaling within Neurons; K: 4 + TBA; G. Niewiadomska; 2015-12-02

 

System

  • Evolution of nervous system and non-vertebrate nervous systems ; TBA; K. Turlejski; 2016-12-09 (starts at 10 a.m.)
  • Anatomy of mammalian nervous system; B: 7 ; M. Malinowska; 2015-12-16
  • The development of nervous system and stem cells; B: 23 P: 22; M. Zawadzka; 2015-01-13 (cancelled)

 

Sensory

  • Auditory system; B: 11 P: 13; K. Burnat; 2016-01-20
  • Chemical senses: olfactory and taste systems ; B: 8  P: 15; R. Dzawadian; 2016-01-27
  • Somatic sensory system; B: 12 P: 9; M. Kossut; 2016-02-17
  • Pain and pain control; B: 12 P: 10; B. Sadowski; 2016-02-24
  • Eye and visual system; B: 9 P: 11; W. Waleszczyk; 2016-03-09 (cancelled)
  • High-Level visual processing – attention and cognition; B: 10 P: 12; A. Wróbel; 2016-03-02

 

Motor

  • Spinal and supraspinal control of movement and locomotion; Kandel: 34,35,36,42, 43;  U. Sławińska; 2016-03-16
  • Control of voluntary movements; Kandel: 33, 37, 38, 40, 41, 42; J. Czarkowska; 2016-03-23

 

Complex

  • The integrative role of hypothalamus; TBA; K. Turlejski; 2016-03-30
  • Emotions and Motivation ; B: 16,18 P: 29; E. Knapska;2016-04-06
  • Speech and Language ; B: 20 P: 27; E. Szeląg; 2016-04-27
  • Learning and memory from system perspective ; B: 24 P: 31; M. Węsierska; 2016-04-20
  • Spatial Memory and Navigation; K: 65, 67R. Czajkowski; 2016-04-13
  • Molecular Mechanisms of Learning and Memory ; B: 25 P: 31; K. Radwańska; 2016-05-04, 2016-05-11
  • Brain rhythms, sleep, dreaming; B: 19 P: 28; 2016-05-11 (cancelled)
  • Association cortex, Attention and Consciousness; B: 21 P: 26; E.Kublik; 2016-05-18

 

Pathology

  • Mental Illness – Anxiety Disorders, Affective Disorders, Schizophrenia; B: 22; A. Barczak (IMDiK); 2016-05-25 (cancelled)
  • Aging and age related pathology (Alzheimer’s and Parkinson disease); K: 59; G. Niewiadomska; 2016-06-01
  • Molecular basis of neurodegenerative disorders; TBA; U. Wojda; 2016-06-08
  • Addiction and drug abuse; TBA; K. Radwańska; 2016-06-15

 

 

B - Neuroscience: Exploring the Brain, 4th Edition [2015] Mark F. Bear

P - Neuroscience, 5th Edition [2011] Dale Purves

K – Principles of Neural Science, 5th Edition [2013] Eric Kandel

 

Additional topics:

  • Repair and neuroregeneration
  • Addiction and drug abuse

Lectures in biochemistry and molecular biology 2014/2015

From molecule to cell

 

  1. Protein structure and fuction  

 

  • Structure and function of proteins S. Pikuła October 8, 2014
  • Protein synthesis M. Dziembowska October 15, 2014
  • Posttranslational modifications of proteins and their functional significance A. Filipek October 22, 2014
  • Proteomics S. Pikuła October 29, 2014

 

  1. Biological membranes – structure and function

 

  • Structure and function of cellular membrane K. Kwiatkowska November 5, 2014
  • Endocytosis M. Miączyńska November 12, 2014
  • Exocytic pathways in eukaryotic cells T. Prószyński November 19, 2014
  • Membrane transport (parts 1 and 2) K. Nałęcz  November 26 and December 3, 2014

 

  1. Cellular metabolism - regulation and dysfunction

 

  • Bioenergetics L. Wojtczak  December 10, 2014
  • Dysfunction of mitochondria and their effects for the cell J. Szczepanowska December 17, 2014
  • Principles of intracellular calcium signaling K. Zabłocki  January 7, 2015
  • Store-operated calcium entry; discovery and understanding of the molecular mechanism K. Zabłocki January 14, 2015
  • Pathomechanisms of diabetes type 2 A. Dobrzyń January 21, 2015

 

  1. Cell motility

 

  • Structure and function of cytoskeleton D. Włoga February 18, 2015
  • Molecular mechanisms of cell motility – molecular motors A. Kasprzak February 25, 2015
  • Mechanisms of cellular migration J. Rędowicz March 4, 2015

 

  1. Genetic information and cellular cycle

 

  • Regulatory mechanisms of transcription B. Kamińska March 11, 2015
  • Transcriptional factors T. Wilanowski March 18, 2015
  • Epigenetic mechanisms of regulation of gene expression B. Kamińska March 25, 2015
  • DNA methylation in control of gene expression W. Leśniak April 1, 2015
  • Cancerogenesis K. Piwocka April 8, 2015
  • Determinants longevity and aging G. Mosieniak April 15, 2015

 

  1. Methods in cell biology, tissue engineering

 

  • Imaging of structures and processes in cells and tissues (part 1 and 2) G. Wilczyński April 22 and 29, 2015
  • Imaging of cellular signaling P. Pomorski May 6, 2015
  • Induced pluripotent stem cells and tissue engineering U. Wojda May 13, 2015
  • Inducible gene expression in transgenic animals W. Konopka May 20, 2015
  • Genetic modifications of rodents  A. Klejman May 27, 2015
  • Regulatory genomics M. Dąbrowski June 3, 2015

 

 


Lectures in the field of Neurobiology  

in academic year 2013/2014

(all lectures are in Polish)

 

I. Nerve cell and its function (6 lectures)

coordinator Małgorzata Skup

  • Nerve cells- structure of the synapses   (M. Skup  05.10)
  • Properties of neuronal membrane – membrane potential, action potential, electrical and electro-chemical signal propagation (P. Boguszewski 09.10)
  • Pre- and postsynaptic membrane (M. Skup 30.10)
  • Neurotransmitters and their receptors (P. Boguszewski 06.11)
  • Communication within neuron  (G. Niewiadomska 13.11)
  • Glia – partner of neurons ( M. Skup 20.11)
  • Blood brain-barrier (K. Nałęcz  27.11)
  • Neural stem cells (M. Zawadzka 04.12)

 

II. Evolution, development and anatomy of the nervous system  (5 lectures)

   +workshops run by G. Niewiadomska i G. Wilczyński *

   coordinator Krzysztof Turlejski

  • Evolution of the central nervous system (K. Turlejski 11.12 )
  • Development of nervous system and neurogenesis (K. Turlejski 18.12)
  • Sensory systems – visual, somatosensory, auditory, gustatory and olfactory systems (K. Turlejski 8.01)
  • Generation of movement and motor control (K. Turlejski 15.01).
  • Systems generating and integrating emotions and decisions (K. Turlejski 15.01)

 

   III. Sensory systems: vision, touch and pain (4 lectures)

               Coordinator Wioletta Waleszczyk

  • Touch. Somatosensory cortex – function and plasticity (M.Kossut 22.01)
  • Vision. Processing of visual information. Malfunctions and plasticity of the  visual system  (W.Waleszczyk 29.01)
  • Pain – phylogenesis, ontogeny , anatomy. Physiological pain (B. Sadowski 19.02)
  •  Modulation of pain sensation. Role of opioids. Pain and brain plasticity, phantom pains (B. Sadowski 26.02)

 

IV. Motor system (3 lectures)

coordinator Julita Czarkowska-Bauch

  • Neuro-muscular system: organization of movement, muscles and motor units; spinal reflexes; control of posture (U. Sławińska (05.03)
  • Control of locomotion:  role of  spinal cord, cerebellum and cerebral cortex ( H. Majczyński 12.03)
  • Spinal reflexes and voluntary movemets: role of motor cortex, cerebellum and basal ganglia (J. Czarkowska-Bauch 19.03)

 

V. Emotions, learning and memory (7 lectures)

        coordinator Elżbieta Szeląg

  • Motivation, emotion, anxiety ( E. Knapska 26.03)
  • Cellular mechanisms of memory – synaptic plasticity, modification of neuronal network  and synaptogenesis (M. Liguz-Lęcznar  02.04)
  • Language – processing and language disorders ( E. Szeląg 09. 04.)
  • Declarative memory: mechanisms and anatomical substrate ( M. Węsierska 16.04)
  • Modeling of neuronal network  ( D.Wójcik  23.04)
  • Molecular substrate of memory ( K. Radwańska 30.04.)
  • Brain and consciousness ( A. Wróbel 07.05)

 

          VI. Aging and pathologies of the nervous system (3 lectures)

  • Aging of the nervous system  (G. Niewiadomska ,14.05)
  • Pathologies of the nervous  system –  The role of microglia in brain function in physiology and pathology (B.Kamińska 21. 05)
  • Neurodegenerative deseases - diagnostic methods and  therapeutic strategies (U. Wojda 28.05)

(2 semesters – 28 lectures. The cycle is repeated every second year)

*Workshops of neuroanatomy will be held from the first week of December, for 6 weeks. The courses, lasting from 1.5 to 2 hours may be attended by up to 6 people. On the same day two groups may be held. In total, 12 people can participate in workshops.

Prof. dr hab. Daniel K. Wójcik
Head of the PhD Studies

Prof. Daniel K. Wójcik

 

PhD Studies Office
mgr Katarzyna Gardocka
studia.doktoranckie@nencki.gov.pl
tel: +48 22 5892215

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